Michelle (Shelley) McGuire

• Maternal/infant nutrition
• Human milk composition
• Breastfeeding
• Milk microbiome
• Lipids
• Postpartum anovulation
• International nutrition
• Leprosy

• Donovan SM, Abrams SA, Azad MB, Belfort MB, Bode L, Carlson SE, Dallas DC, Hettinga K, Jarvinen-Seppo K, Kim J, Lebrilla CB, McGuire MK, Sela DA, Neu J. (2022) Summary of the joint NIH and FDA workshop titled Exploring the Science Surrounding the Safe Use of Bioactive Ingredients in Infant Formula: Considerations for an Assessment Framework. J Pediatr, doi.org/10.1016/j.jpeds.2022.11.027.
• Wilk V, McGuire MK, Roe A. (2022) Early life beef consumption patterns are related to cognitive outcomes at 1-5 years of age. Nutrients, 14(21): 4497. doi: 10.3390/nu14214497.
• Martin MA, Keith M, Pace RM, Williams JE, Ley SH, Barbosa-Leiker C, Caffe B, Smith CB, Kunkle A, Lackey KA, Navarrete AD, Pace CDW, Gogel AC, Eisenberg DTA, Fehrenkamp BD, McGuire MA, McGuire MK, Meehan CL, Brindle EB. (2022) SARS-CoV-2 specific antibody trajectories in mothers and infants over two months following maternal infection. Front Immunol, 13:1015002. doi: 10.3389/fimmu.2022.1015002.
• Mogaka JN, Owuor PM, Odhiambo S, Waterman S, McGuire MK, Fuchs JF, Attia S. (2022) Investigating the impact of Moringa oleifera on Kenyan maternal and infant health: A cluster randomized single-blinded controlled trial protocol. J Pediatr Gastroenterol Nutr. JPGN Reports: Aug 2022; 3(3), e237. doi: 10.1097/PG9.0000000000000237.
• Pace RM, Williams JE, Jarvinen KM, Meehan CL, Martin MA, Ley SH, Barbosa-Leiker C, Andres A, Yeruva L, Belfort MB, Caffe B, Navarrete AD, Lackey KA, Pace CDW, Gogel AC, Fehrenkamp BD, Klein M, Young B, Rosen-Carole C, Diaz N, Gaw SL, Flaherman V, McGuire MA, McGuire MK, Seppo A. (2022) Milk from women diagnosed with COVID-19 does not contain SARS-CoV-2 RNA but has persistent levels of SARS-CoV-2-specific IgA antibodies. Front Immunol, 12, 801797.
• COVID-19 Research Prioritization Group on MNCAH. (2021) A global research prioritization exercise on COVID-19 for maternal, newborn, child and adolescent health. J Global Health, 11:05026. doi: 10.7189/jogh.11.04071.
• McGuire MK, McGuire MA. (2021) Microbiomes and childhood malnutrition: What is the evidence? Ann Nutr Metabol, Aug 30:1-13.
• Reyes SM, Allen DL, Williams JE, McGuire MA, McGuire MK, Hay AG, Rasmussen KM. (2021) Pumping supplies alter the microbiome of pumped human milk: An in-home, randomized, crossover trial. Am J Clin Nutr. 2021 114:1960-1970.
• Lackey KA, Fehrenkamp BD, Pace RM, Williams JE, Meehan CL, McGuire MA, McGuire MK. (2021) Breastfeeding beyond twelve months: Is there evidence for health impacts? Ann Rev Nutr. 2021 41: 283-308.
• Pace RM, Williams JE, Robertson B, Lackey KA, Meehan CL, Price WJ, Foster JA, Sellen DW, Kamau-Mbuthia EW, Kamundia EW, Mbugua S, Moore SE, Prentice AM, Kita DG, Kvist LJ, Otoo GE, Ruiz L, Rodriguez JM, Pareja RG, McGuire MA, Bode L, McGuire MK. (2021) Variation in human milk composition is related to differences in milk and infant fecal microbial communities. Microorganisms. 9, 1153.
• Williams JE, McGuire MK, Meehan CL, McGuire MA, Brooker SL, Kamau-Mbuthia EW, Kamundia EW, Mbugua S, Moore SE, Prentice AM, Otoo GE, Rodriguez JM, Pareja RG, Foster JA, Sellen DW, Kita DG, Neibergs HL, Murdoch BM. (2021) Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Genomics, 113:1867-1875.
• Ruiz L, Rubio CA, Carral CG, Quintana EJ, Lackey KA, McGuire MK, Meehan CL, Foster JA, Sellen DW, Kamau EW, Kamundia EW, Mbugua S, Moore SE, Prentice AM, Gindola D, Otoo GE, Pareja RG, Bode L, McGuire MA, Williams J, Rodriguez JM. (2021) Comparison of two approaches for the metataxonomic analysis of the human milk microbiome. Front Cell Infect Microbiol. 11:622550.
• McGuire MK, Randall AZ, Seppo AE, Jarvinen-Seppo K, Meehan CL, Gindola D, Williams J, Sellen DW, Kamau EW, Kamundia EW, Mbugua S, Moore SE, Prentice AM, Foster JA, Otoo GE, Rodriguez JM, Pareja RG, Bode L, McGuire MA, Campo JJ. (2021) Multipathogen analysis of IgA and IgG antigen specificity for selected pathogens in milk produced by women from diverse geographical regions: The INSPIRE Study. Front. Immunol. 11:614372.
• Pace R, Williams JE, Jarvinen K, Belfort M, Pace C, Lackey K, Gogel A, Young B, McGuire MA, Seppo A, McGuire MK. (2021) COVID-19 and human milk: SARS-CoV-2, antibodies, and neutralizing capacity. MBio, 12(1):e03192-20.
• McGuire MK, Seppo A, Goga A, Buonsenso D, Collado MC, Donovan SM, Muller JA, Ofman G, Monroy-Valle M, O’Connor D, Pace RM, Van de Perre P. (2021) Best practices for human milk collection for COVID-19 research. Breastfeeding Medicine, 16(1):1-10.
• McGuire MK, McGuire M. (2021) Mapping the human milk microbiome: impetus for a long-awaited renaissance in maternal and infant nutrition research? (invited commentary) J Nutr, 151(2): 278-80. (1,6)

Michelle (Shelley) McGuire received her bachelor’s in biology from the University of Illinois (1986), a master’s in nutritional sciences from the University of Illinois (1988) and doctorate in human nutrition from Cornell University (1994). Her research focuses primarily on understanding better how maternal diet and nutritional status influence human milk composition and maternal/infant health during breastfeeding. Of particular interest to her research is understanding the importance of dietary lipids to maternal and infant health.

Shelley also has a long-standing interest in understanding the physiologic mechanisms driving the return of ovulatory function during the postpartum period. Recently, Shelley and her colleagues Mark McGuire and Janet Williams (both at the University of Idaho) have become intrigued by the presence and variability of bacteria in human milk (known as the human milk microbiome). As an extension, they are also interested in how the milk microbiome impacts short- and long-term infant health both in the U.S. and globally. Shelley’s research has been funded by a variety of groups including the U.S. Department of Agriculture, National Institutes of Health, National Science Foundation, Bill and Melinda Gates Foundation and commodity groups such as the National Cattlemen’s Beef Association and the Idaho Dairy Commission. McGuire is also passionately committed to bettering human health through the provision of user-friendly, high-quality, evidence-based nutrition information to the press and public.

Shelley is a seasoned science writer, having coauthored two introductory textbooks: one in its third edition (Nutritional Sciences: from Fundamentals to Food, Cengage Published) and the other in its second edition (NUTR, Cengage Publishing).

Shelley lives with her husband (Mark, associate dean of research and director of Idaho Agricultural Experiment Station, University of Idaho) and their Nova Scotia Duck Tolling Retrievers in Moscow, Idaho. When she’s not engaged in teaching, research or service, she enjoys being with her family and friends, traveling, cooking and eating, running, playing the flute, singing and practicing Iyengar yoga.

• Excellence in Nutrition Education Award, American Society for Nutrition, 2018
• Thomas E. Lutz Teaching Excellence Award, Washington State University College of Arts and Sciences, 2016
• National Spokesperson for the American Society for Nutrition, 2008-2017
• Ehrlich-Koldovsky Award, given by the International Society for Research in Human Milk and Lactation to “recognize a young investigator who has begun to make outstanding, original scientific contributions to the study of human milk and lactation,” 2002
• Future Leader Award, International Life Sciences Institute, 2000
• Phi Beta Kappa Honorary (University of Illinois chapter), 1986